Todd Manini

Todd Manini, Ph.D.

Professor; Division Chief Of Clinical And Population Health Integration; Co-Director Of The Claude D. Pepper Older Americans Independence Center

Department: MD-HOBI-BIOMED INFORMATICS
Business Phone: (352) 273-5914
Business Email: tmanini@ufl.edu

About Todd Manini

Since the start of my career, I’ve pursued contributing knowledge on a gerontological understanding of mobility deficits during the aging process and impact resulting from health events in late-life. I have a wealth of experience conducting both observational studies and clinical trials involving frail and low functioning older adults (minority and non-minority) that will support the organization, administration, planning, compliance, standardization, documentation, monitoring and reporting activities in the current study. As an added asset, I am or have been a key part of several consortia that involve behavioral modifications (UO1 AG022376, U01 AG048270), medication/neutriceutical (U01 AG050499), and body composition (U01 AG15013) studies that overlap operational and scientific elements of the current work. I am also actively leading or have led numerous government-sponsored studies that have strong connections to the ROAMM infrastructure (SBIR 261201500014C, R21 AG031974, UO1 AG022376, U01 AG050499, and R01 HL121023). I feel well qualified and I’m excited to undertake the responsibilities of being a co-investigator on this important study.

I currently serve as the Co-Director of the University of Florida’s Claude D. Pepper Older American’s Independence Center (OAIC) and the Director of the T32 Translational Research on Aging and Mobility (TRAM – T32 AG062728) program. I serve as a Professor and Division Chief of Clinical and Population Health Integration in The Department of Health Outcomes and Biomedical Informatics. Lastly, I am the Co-Leader of the Data Science and Applied Technology Core of the UF OAIC. In these roles, I lead an interdisciplinary team of investigators, staff and trainees. I currently lead both clinical trials and observational studies involving cognitive and physical impairments in older adults. In these studies, besides conducting rigorous science, I manage staff, oversee the finances, ensure regulatory compliance, monitor measurement standardization, and report data and safety information for these programs. I involve trainees at all levels for them to gain an appreciation of not just the science methods, but the overall operations of managing a complex primary data collection research program. I also preach rigorous data collection procedures and transparency throughout the scientific process. As an added asset, I am or was a key part of several consortia that involve behavioral modifications (UO1 AG022376, U01 AG048270), medication/nutraceutical (U01 AG050499), body composition (U01 AG15013) studies that encompass both operational and scientific elements that are matched to career development goals. My collaborative nature and diverse experiences have prepared me well to closely integrate with the team while being conscience of timely deliverables.

I’ve mentored or coached 42 men and women at various stages of their careers (post-doctoral fellows, pre-doctoral students and faculty). I also currently serve as a co-primary mentor and co-mentor of post-doctoral fellows in the T32 TRAM program in which I am Principal Investigator. In the past 5 years, I’ve served as the primary mentor of six post-doctoral fellows, one of which remain an active part of our research team. I’ve served as the primary or co-primary mentor for six doctoral students, five of which have subsequently gone on to either tenure-track faculty positions or post-doctoral positions. Of note, one of my recent doctoral students was accepted at John’s Hopkins Bloomberg School of Public Health and was recently promoted to a faculty position in the Bloomberg School of Public Health. Another formal doctoral student, who worked as part of our core, is currently employed at Google’s research and development team. My goal for these advanced scientists is to train and instill the Gerontological philosophies— preservation of function in conjunction with chronic disease management— to a variety of researchers and practitioners in health-related disciplines. As such, I mentor them on how to incorporate gerontology and geriatrics measures into their domain.

Accomplishments

Associate Editor
2021-current · Journals of Gerontology: Medical Sciences
Division Chief of Epidemiology and Data Science in Gerontology
2019-2021 · University of Florida, Department of Aging & Geriatric Research
Fellow of the Gerontological Society of America (FGSA)
2017 · Gerontological Society of America
Chair of the American College of Sports Medicine Strategic Health Initiative on Aging
2016-2021 · American College of Sports Medicine
NIH Standing Study Section member
2014-2018 · Standing member: Neurological, Aging & Musculoskeletal Epidemiology (NAME)
Adjunct Professor
2011-current · Department of Rehabilitation Sciences
Exemplary Teachers Award
2011 · University of Florida
Assistant Professor Excellence Award
2010 · University of Florida
Adjunct Professor
2009-current · Department of Epidemiology
Fellow of the American College of Sports Medicine (FACSM)
2009 · American College of Sports Medicine
Adjunct Professor
2008-current · Department of Applied Physiology & Kinesiology

Teaching Profile

Courses Taught
2016-2019,2021-2022
GMS6485 Population Based Research on Aging
2012-2016,2021
PHC7980 Research for Doctoral Dissertation
2014-2015
GMS6417 Integrative Aging Physiology
2015
GMS6845 Clinical & Translational Research Practicum
2011-2013,2015-2022,2021-2022
PHC7979 Advanced Research
2013
CLP7980 Research for Doctoral Dissertation
2010-2012
PHC6003 Epidemiology of Chronic Diseases and Disability
2011
PHC6905 Independent Study
2009
APK7108 Environmental Stress Exercise Physiology
2021
GMS6771 Clinical Neuroscience of Aging
2021
GMS6090 Research in Medical Sciences
2021
GMS5905 Special Topics in Biomedical Sciences
2021
PHC7918 Independent Study
2023-2024
GMS6848 Ensuring Rigor and Reproducibility in Clinical and Translational Research

Publications

Academic Articles
2024
Body composition and body mass index are independently associated with widespread pain and experimental pain sensitivity in older adults: a pilot investigation.
Frontiers in pain research (Lausanne, Switzerland). 5 [DOI] 10.3389/fpain.2024.1386573. [PMID] 39015155.
2024
ChatGPT’s Role in Gerontology Research.
The journals of gerontology. Series A, Biological sciences and medical sciences. 79(9) [DOI] 10.1093/gerona/glae184. [PMID] 39046716.
2024
Enhancing EHR Systems with data from wearables: An end-to-end Solution for monitoring post-Surgical Symptoms in older adults
Proceedings of the 30th Annual International Conference on Mobile Computing and Networking. 2282-2289 [DOI] 10.1145/3636534.3698118.
2024
Enhancing EHR Systems with data from wearables: An end-to-end Solution for monitoring post-Surgical Symptoms in older adults.
ArXiv. [PMID] 39575122.
2024
Fracture discrimination capability of ulnar flexural rigidity measured via Cortical Bone Mechanics Technology: study protocol for The STRONGER Study.
JBMR plus. 8(1) [DOI] 10.1093/jbmrpl/ziad002. [PMID] 38690126.
2024
Identifying barriers and facilitators for using a smartwatch to monitor health among older adults.
Educational gerontology. 50(4):282-295 [DOI] 10.1080/03601277.2023.2260970. [PMID] 38737621.
2024
Individual joint contributions to forward propulsion are not related to stability during walking in young or older adults.
Gait & posture. 114:167-174 [DOI] 10.1016/j.gaitpost.2024.09.015. [PMID] 39341103.
2024
Longitudinal associations of life space mobility and domain-specific cognitive measures in ACTIVE.
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition. 1-16 [DOI] 10.1080/13825585.2024.2413720. [PMID] 39396242.
2024
Perspectives on the COVID-19 pandemic and life-space mobility in older adults.
Journal of the American Geriatrics Society. 72(11):3448-3456 [DOI] 10.1111/jgs.19118. [PMID] 39134366.
2024
Prefrontal cortical activity during uneven terrain walking in younger and older adults.
Frontiers in aging neuroscience. 16 [DOI] 10.3389/fnagi.2024.1389488. [PMID] 38765771.
2024
Protocol for a home-based self-delivered prehabilitation intervention to proactively reduce fall risk in older adults: a pilot randomized controlled trial of transcranial direct current stimulation and motor imagery.
Pilot and feasibility studies. 10(1) [DOI] 10.1186/s40814-024-01516-1. [PMID] 38877595.
2024
Resting state brain network segregation is associated with walking speed and working memory in older adults.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2024.05.07.592861. [PMID] 38766046.
2024
Use of Minimally Invasive Methods to Assess Fuel Utilization and Circadian Rhythms in Older Adults.
Journal of visualized experiments : JoVE. (203) [DOI] 10.3791/64628. [PMID] 38251713.
2023
Associations of Total Body Fat Mass and Skeletal Muscle Index with All-Cause and Cancer-Specific Mortality in Cancer Survivors.
Cancers. 15(4) [DOI] 10.3390/cancers15041081. [PMID] 36831420.
2023
Comparing D3-Creatine Dilution and Dual-Energy X-ray Absorptiometry Muscle Mass Responses to Strength Training in Low-Functioning Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 78(9):1591-1596 [DOI] 10.1093/gerona/glad047. [PMID] 36752568.
2023
Comparison of EEG Source Localization Using Simplified and Anatomically Accurate Head Models in Younger and Older Adults.
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. 31:2591-2602 [DOI] 10.1109/TNSRE.2023.3281356. [PMID] 37252873.
2023
Defining and Measuring Preclinical Mobility Limitation: An Expert Consensus Exercise Informed by a Scoping Review.
The journals of gerontology. Series A, Biological sciences and medical sciences. 78(9):1641-1650 [DOI] 10.1093/gerona/glad143. [PMID] 37300461.
2023
Effect of change of interleukin-6 over time on gait speed response: Results from the lifestyle interventions and independence for elders study.
Mechanisms of ageing and development. 210 [DOI] 10.1016/j.mad.2022.111763. [PMID] 36526102.
2023
Effect of Physical Activity Intervention on Gait Speed by Frailty Condition: A Randomized Clinical Trial.
Journal of the American Medical Directors Association. 24(4):489-496 [DOI] 10.1016/j.jamda.2023.01.023. [PMID] 36878264.
2023
Electrical Brain Activity during Human Walking with Parametric Variations in Terrain Unevenness and Walking Speed.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.07.31.551289. [PMID] 37577540.
2023
Feasibility of a Smartwatch Platform to Assess Ecological Mobility: Real-Time Online Assessment and Mobility Monitor.
The journals of gerontology. Series A, Biological sciences and medical sciences. 78(5):821-830 [DOI] 10.1093/gerona/glad046. [PMID] 36744611.
2023
Hospitalizations during home-based walking exercise interventions in peripheral artery disease: Results from two randomized clinical trials.
Vascular medicine (London, England). 28(6):583-585 [DOI] 10.1177/1358863X231191909. [PMID] 37622748.
2023
Independent and joint associations of cardiorespiratory fitness and lower-limb muscle strength with cardiometabolic risk in older adults.
PloS one. 18(10) [DOI] 10.1371/journal.pone.0292957. [PMID] 37871003.
2023
Media Consumption and COVID-19-Related Precautionary Behaviors During the Early Pandemic: Survey Study of Older Adults.
JMIR formative research. 7 [DOI] 10.2196/46230. [PMID] 37213166.
2023
Muscle Quality in Older Adults: A Scoping Review.
Journal of the American Medical Directors Association. 24(4):462-467.e12 [DOI] 10.1016/j.jamda.2023.02.012. [PMID] 36963436.
2023
Uneven terrain versus dual-task walking: differential challenges imposed on walking behavior in older adults are predicted by cognitive and sensorimotor function.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2023.03.14.531779. [PMID] 36993462.
2022
Are Machine Learning Models on Wrist Accelerometry Robust against Differences in Physical Performance among Older Adults?
Sensors (Basel, Switzerland). 22(8) [DOI] 10.3390/s22083061. [PMID] 35459045.
2022
Comparisons Between GPS-based and Self-reported Life-space Mobility in Older Adults.
AMIA … Annual Symposium proceedings. AMIA Symposium. 2022:212-220 [PMID] 37128363.
2022
Effects of Walking Exercise at a Pace With Versus Without Ischemic Leg Symptoms on Functional Performance Measures in People With Lower Extremity Peripheral Artery Disease: The LITE Randomized Clinical Trial.
Journal of the American Heart Association. 11(15) [DOI] 10.1161/JAHA.121.025063. [PMID] 35894088.
2022
Evaluation of the key prescription sequence symmetry analysis assumption using the calcium channel blocker: Loop diuretic prescribing cascade.
Pharmacoepidemiology and drug safety. 31(1):72-81 [DOI] 10.1002/pds.5362. [PMID] 34553438.
2022
Frailty and risk of mortality in older cancer survivors and adults without a cancer history: Evidence from the National Health and Nutrition Examination Survey, 1999-2014.
Cancer. 128(15):2978-2987 [DOI] 10.1002/cncr.34258. [PMID] 35608563.
2022
Kinematic analysis of speed transitions within walking in younger and older adults.
Journal of biomechanics. 138 [DOI] 10.1016/j.jbiomech.2022.111130. [PMID] 35569430.
2022
Uneven terrain treadmill walking in younger and older adults.
PloS one. 17(12) [DOI] 10.1371/journal.pone.0278646. [PMID] 36534645.
2022
Worsening sleep predicts lower life space mobility during the onset of the COVID-19 pandemic.
Journal of the American Geriatrics Society. 70(7):1931-1938 [DOI] 10.1111/jgs.17896. [PMID] 35608359.
2021
Age Differences in Estimating Physical Activity by Wrist Accelerometry Using Machine Learning.
Sensors (Basel, Switzerland). 21(10) [DOI] 10.3390/s21103352. [PMID] 34065906.
2021
Differences in Health-Related Quality of Life Among Adults with a Potential Dihydropyridine Calcium Channel Blocker-Loop Diuretic Prescribing Cascade.
Drugs & aging. 38(7):625-632 [DOI] 10.1007/s40266-021-00868-0. [PMID] 34095980.
2021
Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well-Being: The STRIDE Study.
Journal of the American Geriatrics Society. 69(1):173-179 [DOI] 10.1111/jgs.16854. [PMID] 33037632.
2021
Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery Disease: The LITE Randomized Clinical Trial.
JAMA. 325(13):1266-1276 [DOI] 10.1001/jama.2021.2536. [PMID] 33821898.
2021
Elevated IL-6 and CRP Levels Are Associated With Incident Self-Reported Major Mobility Disability: A Pooled Analysis of Older Adults With Slow Gait Speed.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(12):2293-2299 [DOI] 10.1093/gerona/glab093. [PMID] 33822946.
2021
Evaluation of a Strength-Training Program on Clinical Outcomes in Older Adults.
JAMA. 325(11) [DOI] 10.1001/jama.2021.0298. [PMID] 33724318.
2021
Functional connectivity of key resting state networks and objectively measured physical activity in older adults with joint pain: A pilot study.
Experimental gerontology. 153 [DOI] 10.1016/j.exger.2021.111470. [PMID] 34246732.
2021
Ratings of Perceived Exertion During Walking: Predicting Major Mobility Disability and Effect of Structured Physical Activity in Mobility-Limited Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(10):e264-e271 [DOI] 10.1093/gerona/glab036. [PMID] 33585918.
2021
Reduced Neural Excitability and Activation Contribute to Clinically Meaningful Weakness in Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(4):692-702 [DOI] 10.1093/gerona/glaa157. [PMID] 32588058.
2021
Satisfaction, Usability, and Compliance With the Use of Smartwatches for Ecological Momentary Assessment of Knee Osteoarthritis Symptoms in Older Adults: Usability Study.
JMIR aging. 4(3) [DOI] 10.2196/24553. [PMID] 34259638.
2021
Study Protocol Modeling Evoked Pain in Older African Americans With Knee Osteoarthritis.
Nursing research. 70(5):391-398 [DOI] 10.1097/NNR.0000000000000520. [PMID] 33951704.
2021
Survey-reported medication changes among older adults during the SARS-CoV-2 (COVID-19) pandemic.
Research in social & administrative pharmacy : RSAP. 17(8):1478-1482 [DOI] 10.1016/j.sapharm.2020.11.005. [PMID] 33221267.
2021
Sustained physical activity in peripheral artery disease: Associations with disease severity, functional performance, health-related quality of life, and subsequent serious adverse events in the LITE randomized clinical trial.
Vascular medicine (London, England). 26(5):497-506 [DOI] 10.1177/1358863X21989430. [PMID] 33829920.
2021
The Effect of Sensor Placement and Number on Physical Activity Recognition and Energy Expenditure Estimation in Older Adults: Validation Study.
JMIR mHealth and uHealth. 9(5) [DOI] 10.2196/23681. [PMID] 33938809.
2021
The Temporal Relationship Between Ecological Pain and Life-Space Mobility in Older Adults With Knee Osteoarthritis: A Smartwatch-Based Demonstration Study.
JMIR mHealth and uHealth. 9(1) [DOI] 10.2196/19609. [PMID] 33439135.
2021
Three-Year, Postintervention, Follow-up Comparison of Health Care Resource Utilization and Costs in the Lifestyle Interventions and Independence for Elders (LIFE) Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(2):272-276 [DOI] 10.1093/gerona/glaa088. [PMID] 32270182.
2021
What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium.
The journals of gerontology. Series A, Biological sciences and medical sciences. 76(10):e321-e327 [DOI] 10.1093/gerona/glab183. [PMID] 34166490.
2020
A Simulated Graphical Interface for Integrating Patient-Generated Health Data From Smartwatches With Electronic Health Records: Usability Study.
JMIR human factors. 7(4) [DOI] 10.2196/19769. [PMID] 33124988.
2020
Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults.
Cells. 9(12) [DOI] 10.3390/cells9122579. [PMID] 33276460.
2020
Application of Cut-Points for Low Muscle Strength and Lean Mass in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society. 68(7):1445-1453 [DOI] 10.1111/jgs.16525. [PMID] 32633836.
2020
Application of SDOC Cut Points for Low Muscle Strength for Recovery of Walking Speed After Hip Fracture.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(7):1379-1385 [DOI] 10.1093/gerona/glaa076. [PMID] 32242218.
2020
Application of Selected Muscle Strength and Body Mass Cut Points for the Diagnosis of Sarcopenia in Men and Women With or at Risk for HIV Infection.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(7):1338-1345 [DOI] 10.1093/gerona/glaa083. [PMID] 32301484.
2020
Association between a Deficit Accumulation Frailty Index and Mobility Outcomes in Older Adults: Secondary Analysis of the Lifestyle Interventions and Independence for Elders (LIFE) Study.
Journal of clinical medicine. 9(11) [DOI] 10.3390/jcm9113757. [PMID] 33266358.
2020
Association of Fish Oil and Physical Activity on Mobility Disability in Older Adults.
Medicine and science in sports and exercise. 52(4):859-867 [DOI] 10.1249/MSS.0000000000002195. [PMID] 31688650.
2020
Comparative Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Response to a Physical Activity Intervention in Older Adults: Results From the Lifestyle Interventions and Independence for Elders Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(5):1010-1016 [DOI] 10.1093/gerona/glz120. [PMID] 31070702.
2020
Comparison of a Multi-Component Physical Function Battery to Usual Walking Speed for Assessing Lower Extremity Function and Mobility Limitation in Older Adults.
The journal of nutrition, health & aging. 24(8):906-913 [DOI] 10.1007/s12603-020-1432-2. [PMID] 33009544.
2020
Corrigendum: Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience. 12 [DOI] 10.3389/fnagi.2020.00063. [PMID] 32194394.
2020
Deep CHORES: Estimating Hallmark Measures of Physical Activity Using Deep Learning.
AMIA … Annual Symposium proceedings. AMIA Symposium. 2020:803-812 [PMID] 33936455.
2020
Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes: Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference.
The journals of gerontology. Series A, Biological sciences and medical sciences. 75(7):1317-1323 [DOI] 10.1093/gerona/glz081. [PMID] 30869772.
2020
Evaluation of the Potential Acetylcholinesterase Inhibitor-Induced Rhinorrhea Prescribing Cascade.
Journal of the American Geriatrics Society. 68(2):440-441 [DOI] 10.1111/jgs.16224. [PMID] 31625144.
2020
Healthcare Utilization and Physical Functioning in Older Adults in the United States.
Journal of the American Geriatrics Society. 68(2):266-271 [DOI] 10.1111/jgs.16260. [PMID] 31755551.
2020
Higher dose of resveratrol elevated cardiovascular disease risk biomarker levels in overweight older adults – A pilot study.
Experimental gerontology. 131 [DOI] 10.1016/j.exger.2019.110821. [PMID] 31891746.
2020
Identification of Sarcopenia Components That Discriminate Slow Walking Speed: A Pooled Data Analysis.
Journal of the American Geriatrics Society. 68(7):1419-1428 [DOI] 10.1111/jgs.16524. [PMID] 32633834.
2020
Impact and Lessons From the Lifestyle Interventions and Independence for Elders (LIFE) Clinical Trials of Physical Activity to Prevent Mobility Disability.
Journal of the American Geriatrics Society. 68(4):872-881 [DOI] 10.1111/jgs.16365. [PMID] 32105353.
2020
Impact of Anticholinergic Medication Burden on Mobility and Falls in the Lifestyle Interventions for Elders (LIFE) Study.
Journal of clinical medicine. 9(9) [DOI] 10.3390/jcm9092989. [PMID] 32947839.
2020
Impact of Baseline Fatigue on a Physical Activity Intervention to Prevent Mobility Disability.
Journal of the American Geriatrics Society. 68(3):619-624 [DOI] 10.1111/jgs.16274. [PMID] 31867713.
2020
Innovations in Geroscience to enhance mobility in older adults.
Experimental gerontology. 142 [DOI] 10.1016/j.exger.2020.111123. [PMID] 33191210.
2020
Putative Cut-Points in Sarcopenia Components and Incident Adverse Health Outcomes: An SDOC Analysis.
Journal of the American Geriatrics Society. 68(7):1429-1437 [DOI] 10.1111/jgs.16517. [PMID] 32633824.
2020
Relative contribution of muscle strength, lean mass, and lower extremity motor function in explaining between-person variance in mobility in older adults.
BMC geriatrics. 20(1) [DOI] 10.1186/s12877-020-01656-y. [PMID] 32723298.
2020
Sarcopenia Definition & Outcomes Consortium Defined Low Grip Strength in Two Cross-Sectional, Population-Based Cohorts.
Journal of the American Geriatrics Society. 68(7):1438-1444 [DOI] 10.1111/jgs.16419. [PMID] 32633830.
2020
Sarcopenia Definition: The Position Statements of the Sarcopenia Definition and Outcomes Consortium.
Journal of the American Geriatrics Society. 68(7):1410-1418 [DOI] 10.1111/jgs.16372. [PMID] 32150289.
2020
Secondary care provider attitudes towards patient generated health data from smartwatches.
NPJ digital medicine. 3 [DOI] 10.1038/s41746-020-0236-4. [PMID] 32140569.
2020
The relationship between interleukin-6 levels and physical performance in mobility-limited older adults with chronic low-grade inflammation: The ENRGISE Pilot study.
Archives of gerontology and geriatrics. 90 [DOI] 10.1016/j.archger.2020.104131. [PMID] 32554219.
2020
Trajectories of Short Physical Performance Battery Are Strongly Associated with Future Major Mobility Disability: Results from the LIFE Study.
Journal of clinical medicine. 9(8) [DOI] 10.3390/jcm9082332. [PMID] 32707877.
2020
Transcutaneous Electrical Stimulation on the Submental Area: The Relations of Biopsychological Factors with Maximum Amplitude Tolerance and Perceived Discomfort Level.
Dysphagia. 35(2):301-307 [DOI] 10.1007/s00455-019-10029-6. [PMID] 31209638.
2019
A Case for Promoting Movement Medicine: Preventing Disability in the LIFE Randomized Controlled Trial.
The journals of gerontology. Series A, Biological sciences and medical sciences. 74(11):1821-1827 [DOI] 10.1093/gerona/glz050. [PMID] 30778518.
2019
A comparison of accelerometry analysis methods for physical activity in older adult women and associations with health outcomes over time.
Journal of sports sciences. 37(20):2309-2317 [DOI] 10.1080/02640414.2019.1631080. [PMID] 31195893.
2019
A smartwatch-based framework for real-time and online assessment and mobility monitoring.
Journal of biomedical informatics. 89:29-40 [DOI] 10.1016/j.jbi.2018.11.003. [PMID] 30414474.
2019
Accuracy of Samsung Gear S Smartwatch for Activity Recognition: Validation Study.
JMIR mHealth and uHealth. 7(2) [DOI] 10.2196/11270. [PMID] 30724739.
2019
Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle.
Cells. 8(12) [DOI] 10.3390/cells8121525. [PMID] 31783583.
2019
Blood Flow-restricted Exercise Does Not Induce a Cross-Transfer of Effect: A Randomized Controlled Trial.
Medicine and science in sports and exercise. 51(9):1817-1827 [DOI] 10.1249/MSS.0000000000001984. [PMID] 30913160.
2019
Blood-Flow Restriction Resistance Exercise for Older Adults with Knee Osteoarthritis: A Pilot Randomized Clinical Trial.
Journal of clinical medicine. 8(2) [DOI] 10.3390/jcm8020265. [PMID] 30795545.
2019
Effect of Gastric Acid Suppressants on Response to a Physical Activity Intervention and Major Mobility Disability in Older Adults: Results from the Lifestyle Interventions for Elders (LIFE) Study.
Pharmacotherapy. 39(8):816-826 [DOI] 10.1002/phar.2299. [PMID] 31230397.
2019
Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society. 67(2):261-268 [DOI] 10.1111/jgs.15631. [PMID] 30452084.
2019
Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial.
The journals of gerontology. Series A, Biological sciences and medical sciences. 74(10):1612-1619 [DOI] 10.1093/gerona/gly277. [PMID] 30541065.
2019
Magnitude of and Characteristics Associated With the Treatment of Calcium Channel Blocker-Induced Lower-Extremity Edema With Loop Diuretics.
JAMA network open. 2(12) [DOI] 10.1001/jamanetworkopen.2019.18425. [PMID] 31880802.
2019
Mitochondrial DNA variants and pulmonary function in older persons.
Experimental gerontology. 115:96-103 [DOI] 10.1016/j.exger.2018.11.023. [PMID] 30508565.
2019
Movement-evoked pain: transforming the way we understand and measure pain.
Pain. 160(4):757-761 [DOI] 10.1097/j.pain.0000000000001431. [PMID] 30371555.
2019
Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults (Mind in Motion Study): Hypothesis, Theory, and Methods.
Frontiers in aging neuroscience. 11 [DOI] 10.3389/fnagi.2019.00358. [PMID] 31969814.
2019
Perception of Older Adults Toward Smartwatch Technology for Assessing Pain and Related Patient-Reported Outcomes: Pilot Study.
JMIR mHealth and uHealth. 7(3) [DOI] 10.2196/10044. [PMID] 30912756.
2019
Role of Wearable Accelerometer Devices in Delirium Studies: A Systematic Review.
Critical care explorations. 1(9) [DOI] 10.1097/CCE.0000000000000027. [PMID] 32166280.
2019
The Effects of Electrical Stimulation Pulse Duration on Lingual Palatal Pressure Measures During Swallowing in Healthy Older Adults.
Dysphagia. 34(4):529-539 [DOI] 10.1007/s00455-019-09991-y. [PMID] 30820657.
2019
The Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study.
Nutrients. 11(7) [DOI] 10.3390/nu11071500. [PMID] 31262054.
2019
The Enabling Reduction of Low-Grade Inflammation in Seniors (ENRGISE) Pilot Study: Screening Methods and Recruitment Results.
The journals of gerontology. Series A, Biological sciences and medical sciences. 74(8):1296-1302 [DOI] 10.1093/gerona/gly204. [PMID] 30202946.
2019
Translating the Lifestyle Interventions and Independence for Elders Clinical Trial to Older Adults in a Real-World Community-Based Setting.
The journals of gerontology. Series A, Biological sciences and medical sciences. 74(6):924-928 [DOI] 10.1093/gerona/gly152. [PMID] 30010808.
2019
Voluntary vs Electrically Stimulated Activation in Age-Related Muscle Weakness.
JAMA network open. 2(9) [DOI] 10.1001/jamanetworkopen.2019.12052. [PMID] 31553466.
2019
Wearable Technology To Reduce Sedentary Behavior And CVD Risk In Older Adults: A Pilot Randomized Clinical Trial.
Clinical interventions in aging. 14:1817-1828 [DOI] 10.2147/CIA.S222655. [PMID] 31695350.
2018
A Comparison of Self-report Indices of Major Mobility Disability to Failure on the 400-m Walk Test: The LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(4):513-518 [DOI] 10.1093/gerona/glx153. [PMID] 28958023.
2018
Activity and Circadian Rhythm of Sepsis Patients in the Intensive Care Unit.
… IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics. 2018:17-20 [DOI] 10.1109/BHI.2018.8333359. [PMID] 30411088.
2018
Associations between ACE-Inhibitors, Angiotensin Receptor Blockers, and Lean Body Mass in Community Dwelling Older Women.
Journal of aging research. 2018 [DOI] 10.1155/2018/8491092. [PMID] 29670769.
2018
Comment on: “Pitfalls in the measurement of muscle mass: a need for a reference standard” by Buckinx et al.
Journal of cachexia, sarcopenia and muscle. 9(7):1269-1271 [DOI] 10.1002/jcsm.12372. [PMID] 30680964.
2018
Community-Based Activity and Sedentary Patterns Are Associated With Cognitive Performance in Mobility-Limited Older Adults.
Frontiers in aging neuroscience. 10 [DOI] 10.3389/fnagi.2018.00341. [PMID] 30498440.
2018
Diet and Activity Assessments and Interventions Using Technology in Older Adults.
American journal of preventive medicine. 55(4):e105-e115 [DOI] 10.1016/j.amepre.2018.06.005. [PMID] 30241621.
2018
Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.
Journal of the American Geriatrics Society. 66(6):1172-1179 [DOI] 10.1111/jgs.15369. [PMID] 29637543.
2018
Effect of 24-month physical activity on cognitive frailty and the role of inflammation: the LIFE randomized clinical trial.
BMC medicine. 16(1) [DOI] 10.1186/s12916-018-1174-8. [PMID] 30352583.
2018
Effect of Physical Activity on Frailty: Secondary Analysis of a Randomized Controlled Trial.
Annals of internal medicine. 168(5):309-316 [DOI] 10.7326/M16-2011. [PMID] 29310138.
2018
Effects of 90 Days of Resveratrol Supplementation on Cognitive Function in Elders: A Pilot Study.
Journal of alternative and complementary medicine (New York, N.Y.). 24(7):725-732 [DOI] 10.1089/acm.2017.0398. [PMID] 29583015.
2018
Effects of Fermented Papaya Preparation (FPP) on Safety Outcomes in Older Adults – A Short Report of a Placebo-Controlled Clinical Trial.
The Journal of frailty & aging. 7(2):142-146 [DOI] 10.14283/jfa.2018.6. [PMID] 29741201.
2018
Evaluating Accelerometry Thresholds for Detecting Changes in Levels of Moderate Physical Activity and Resulting Major Mobility Disability.
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(5):660-667 [DOI] 10.1093/gerona/glx132. [PMID] 28977340.
2018
Evidence-based nutritional and pharmacological interventions targeting chronic low-grade inflammation in middle-age and older adults: A systematic review and meta-analysis.
Ageing research reviews. 46:42-59 [DOI] 10.1016/j.arr.2018.05.004. [PMID] 29803716.
2018
Gait Speed and Mobility Disability: Revisiting Meaningful Levels in Diverse Clinical Populations.
Journal of the American Geriatrics Society. 66(5):954-961 [DOI] 10.1111/jgs.15331. [PMID] 29608795.
2018
Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(5):688-694 [DOI] 10.1093/gerona/glx231. [PMID] 29490012.
2018
Meta-analysis identifies mitochondrial DNA sequence variants associated with walking speed.
GeroScience. 40(5-6):497-511 [DOI] 10.1007/s11357-018-0043-x. [PMID] 30338417.
2018
Mitochondrial DNA m.13514G>A heteroplasmy is associated with depressive symptoms in the elderly.
International journal of geriatric psychiatry. 33(10):1319-1326 [DOI] 10.1002/gps.4928. [PMID] 29984425.
2018
Mitochondrial DNA m.3243A > G heteroplasmy affects multiple aging phenotypes and risk of mortality.
Scientific reports. 8(1) [DOI] 10.1038/s41598-018-30255-6. [PMID] 30089816.
2018
Mitochondrial DNA Sequence Variants Associated With Blood Pressure Among 2 Cohorts of Older Adults.
Journal of the American Heart Association. 7(18) [DOI] 10.1161/JAHA.118.010009. [PMID] 30371200.
2018
Self-Reported Physical Function As a Predictor of Hospitalization in the Lifestyle Interventions and Independence for Elders Study.
Journal of the American Geriatrics Society. 66(10):1927-1933 [DOI] 10.1111/jgs.15468. [PMID] 30281796.
2018
Social Participation Modifies the Effect of a Structured Physical Activity Program on Major Mobility Disability Among Older Adults: Results From the LIFE Study.
The journals of gerontology. Series B, Psychological sciences and social sciences. 73(8):1501-1513 [DOI] 10.1093/geronb/gbx051. [PMID] 28482106.
2018
The Influence of Physical Activity and Sedentary Behavior on Living to Age 85 Years Without Disease and Disability in Older Women.
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(11):1525-1531 [DOI] 10.1093/gerona/glx222. [PMID] 29165626.
2018
Transition Icons for Time-Series Visualization and Exploratory Analysis.
IEEE journal of biomedical and health informatics. 22(2):623-630 [DOI] 10.1109/JBHI.2017.2704608. [PMID] 28534797.
2018
Wrist accelerometer shape feature derivation methods for assessing activities of daily living.
BMC medical informatics and decision making. 18(Suppl 4) [DOI] 10.1186/s12911-018-0671-1. [PMID] 30537957.
2017
A New Adaptive Home-based Exercise Technology among Older Adults Living in Nursing Home: A Pilot Study on Feasibility, Acceptability and Physical Performance.
The journal of nutrition, health & aging. 21(7):819-824 [DOI] 10.1007/s12603-016-0820-0. [PMID] 28717812.
2017
A new approach to disentangle genetic and epigenetic components on disease comorbidities: studying correlation between genotypic and phenotypic disease networks.
Procedia computer science. 110:453-458 [DOI] 10.1016/j.procs.2017.06.119. [PMID] 32318124.
2017
Association between age-related reductions in testosterone and risk of prostate cancer-An analysis of patients’ data with prostatic diseases.
International journal of cancer. 141(9):1783-1793 [DOI] 10.1002/ijc.30882. [PMID] 28699177.
2017
Association Between Structured Physical Activity and Sedentary Time in Older Adults.
JAMA. 318(3):297-299 [DOI] 10.1001/jama.2017.7203. [PMID] 28719683.
2017
Association of Accelerometer-Measured Physical Activity With Leukocyte Telomere Length Among Older Women.
The journals of gerontology. Series A, Biological sciences and medical sciences. 72(11):1532-1537 [DOI] 10.1093/gerona/glx037. [PMID] 28329327.
2017
Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study.
Journal of the American Heart Association. 6(12) [DOI] 10.1161/JAHA.117.007215. [PMID] 29197830.
2017
Associations of Accelerometer-Measured and Self-Reported Sedentary Time With Leukocyte Telomere Length in Older Women.
American journal of epidemiology. 185(3):172-184 [DOI] 10.1093/aje/kww196. [PMID] 28100466.
2017
Blood flow restricted resistance training in older adults at risk of mobility limitations.
Experimental gerontology. 99:138-145 [DOI] 10.1016/j.exger.2017.10.004. [PMID] 28987643.
2017
Can KAATSU Exercise Cause Rhabdomyolysis?
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine. 27(1):e1-e2 [DOI] 10.1097/JSM.0000000000000309. [PMID] 26882107.
2017
Change in Physical Activity and Sitting Time After Myocardial Infarction and Mortality Among Postmenopausal Women in the Women’s Health Initiative-Observational Study.
Journal of the American Heart Association. 6(5) [DOI] 10.1161/JAHA.116.005354. [PMID] 28507059.
2017
Device-Measured Physical Activity As a Predictor of Disability in Mobility-Limited Older Adults.
Journal of the American Geriatrics Society. 65(10):2251-2256 [DOI] 10.1111/jgs.15037. [PMID] 28799216.
2017
Dose of physical activity, physical functioning and disability risk in mobility-limited older adults: Results from the LIFE study randomized trial.
PloS one. 12(8) [DOI] 10.1371/journal.pone.0182155. [PMID] 28820909.
2017
Dynapenia and Metabolic Health in Obese and Nonobese Adults Aged 70 Years and Older: The LIFE Study.
Journal of the American Medical Directors Association. 18(4):312-319 [DOI] 10.1016/j.jamda.2016.10.001. [PMID] 27914851.
2017
Effect of Physical Activity on Self-Reported Disability in Older Adults: Results from the LIFE Study.
Journal of the American Geriatrics Society. 65(5):980-988 [DOI] 10.1111/jgs.14742. [PMID] 28168689.
2017
Effect of Physical Activity versus Health Education on Physical Function, Grip Strength and Mobility.
Journal of the American Geriatrics Society. 65(7):1427-1433 [DOI] 10.1111/jgs.14804. [PMID] 28221668.
2017
Effects of a Long-Term Physical Activity Program on Activity Patterns in Older Adults.
Medicine and science in sports and exercise. 49(11):2167-2175 [DOI] 10.1249/MSS.0000000000001340. [PMID] 29045323.
2017
Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 42(1):89-92 [DOI] 10.1139/apnm-2016-0224. [PMID] 28002685.
2017
Effects of Popular Diets without Specific Calorie Targets on Weight Loss Outcomes: Systematic Review of Findings from Clinical Trials.
Nutrients. 9(8) [DOI] 10.3390/nu9080822. [PMID] 28758964.
2017
ENabling Reduction of Low-grade Inflammation in SEniors Pilot Study: Concept, Rationale, and Design.
Journal of the American Geriatrics Society. 65(9):1961-1968 [DOI] 10.1111/jgs.14965. [PMID] 28734043.
2017
Exercise’s effect on mobility disability in older adults with and without obesity: The LIFE study randomized clinical trial.
Obesity (Silver Spring, Md.). 25(7):1199-1205 [DOI] 10.1002/oby.21860. [PMID] 28653499.
2017
Impact of chemotherapy on medium-term physical function and activity of older breast cancer survivors, and associated biomarkers.
Journal of geriatric oncology. 8(1):69-75 [DOI] 10.1016/j.jgo.2016.09.004. [PMID] 27743848.
2017
Leisure-time physical activity and leukocyte telomere length among older women.
Experimental gerontology. 95:141-147 [DOI] 10.1016/j.exger.2017.05.019. [PMID] 28552815.
2017
Metabolic costs of daily activity in older adults (Chores XL) study: design and methods.
Contemporary clinical trials communications. 6:1-8 [DOI] 10.1016/j.conctc.2017.02.003. [PMID] 28649668.
2017
Osteoporosis in the Women’s Health Initiative: Another Treatment Gap?
The American journal of medicine. 130(8):937-948 [DOI] 10.1016/j.amjmed.2017.02.042. [PMID] 28366425.
2017
Predictors of Change in Physical Function in Older Adults in Response to Long-Term, Structured Physical Activity: The LIFE Study.
Archives of physical medicine and rehabilitation. 98(1):11-24.e3 [DOI] 10.1016/j.apmr.2016.07.019. [PMID] 27568165.
2017
Prognostic Value of Braden Activity Subscale for Mobility Status in Hospitalized Older Adults.
Journal of hospital medicine. 12(6):396-401 [DOI] 10.12788/jhm.2748. [PMID] 28574527.
2017
Surveying predictors of late-life longitudinal change in daily activity energy expenditure.
PloS one. 12(10) [DOI] 10.1371/journal.pone.0186289. [PMID] 29040301.
2017
Systemic inflammation, body composition, and physical performance in old community-dwellers.
Journal of cachexia, sarcopenia and muscle. 8(1):69-77 [DOI] 10.1002/jcsm.12134. [PMID] 27897412.
2017
The effect of intervening hospitalizations on the benefit of structured physical activity in promoting independent mobility among community-living older persons: secondary analysis of a randomized controlled trial.
BMC medicine. 15(1) [DOI] 10.1186/s12916-017-0824-6. [PMID] 28347337.
2017
The Need for Standardized Assessment of Muscle Quality in Skeletal Muscle Function Deficit and Other Aging-Related Muscle Dysfunctions: A Symposium Report.
Frontiers in physiology. 8 [DOI] 10.3389/fphys.2017.00087. [PMID] 28261109.
2017
Wearable technology to reduce sedentary behavior and CVD risk in older adults: design of a randomized controlled trial.
Contemporary clinical trials communications. 6:122-126 [DOI] 10.1016/j.conctc.2017.04.003. [PMID] 28944304.
2016
Actigraphy features for predicting mobility disability in older adults.
Physiological measurement. 37(10):1813-1833 [PMID] 27653966.
2016
Analysis and Interpretation of Accelerometry Data in Older Adults: The LIFE Study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 71(4):521-8 [DOI] 10.1093/gerona/glv204. [PMID] 26515258.
2016
Anticholinergic Drug Use and Risk to Cognitive Performance in Older Adults with Questionable Cognitive Impairment: A Cross-Sectional Analysis.
Drugs & aging. 33(11):809-818 [PMID] 27638818.
2016
Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability.
The journals of gerontology. Series A, Biological sciences and medical sciences. 71(5):656-62 [DOI] 10.1093/gerona/glw001. [PMID] 26888433.
2016
Depressive symptom severity is associated with increased cortical thickness in older adults.
International journal of geriatric psychiatry. 31(4):325-33 [DOI] 10.1002/gps.4324. [PMID] 26205176.
2016
Effectiveness of blood flow restricted exercise compared with standard exercise in patients with recurrent low back pain: study protocol for a randomized controlled trial.
Trials. 17 [DOI] 10.1186/s13063-016-1214-7. [PMID] 26867541.
2016
Evaluating Walking Intensity with Hip-Worn Accelerometers in Elders.
Medicine and science in sports and exercise. 48(11):2216-2221 [PMID] 27327031.
2016
Genetic Moderators of the Impact of Physical Activity on Depressive Symptoms.
The Journal of frailty & aging. 5(1):6-14 [DOI] 10.14283/jfa.2016.76. [PMID] 26980363.
2016
Hospitalizations During a Physical Activity Intervention in Older Adults at Risk of Mobility Disability: Analyses from the Lifestyle Interventions and Independence for Elders Randomized Clinical Trial.
Journal of the American Geriatrics Society. 64(5):933-43 [DOI] 10.1111/jgs.14114. [PMID] 27225353.
2016
Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle.
Oncotarget. 7(33):52695-52709 [DOI] 10.18632/oncotarget.10685. [PMID] 27447862.
2016
In-Hospital Mobility Variations Across Primary Diagnoses Among Older Adults.
Journal of the American Medical Directors Association. 17(5):465.e1-8 [DOI] 10.1016/j.jamda.2016.02.003. [PMID] 26971132.
2016
Letter to the editor: results from a Web-based survey to identify dynapenia screening tools and risk factors.
Journal of cachexia, sarcopenia and muscle. 7(4):499-500 [DOI] 10.1002/jcsm.12128. [PMID] 27625921.
2016
Long-Term Cigarette Smoking Trajectories Among HIV-Seropositive and Seronegative MSM in the Multicenter AIDS Cohort Study.
AIDS and behavior. 20(8):1713-21 [DOI] 10.1007/s10461-016-1343-8. [PMID] 26922718.
2016
Metabolic Rate and Perceived Exertion of Walking in Older Adults With Idiopathic Chronic Fatigue.
The journals of gerontology. Series A, Biological sciences and medical sciences. 71(11):1444-1450 [PMID] 27271253.
2016
Physical impairment and body weight history in postmenopausal women: the Women’s Health Initiative.
Public health nutrition. 19(17):3169-3177 [PMID] 27269298.
2016
Socioeconomic differences in the benefits of structured physical activity compared with health education on the prevention of major mobility disability in older adults: the LIFE study.
Journal of epidemiology and community health. 70(9):930-3 [DOI] 10.1136/jech-2016-207321. [PMID] 27060177.
2016
Using symbolic aggregate approximation (SAX) to visualize activity transitions among older adults.
Physiological measurement. 37(11):1981-1992 [PMID] 27754973.
2015
A physical activity intervention to treat the frailty syndrome in older persons-results from the LIFE-P study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(2):216-22 [DOI] 10.1093/gerona/glu099. [PMID] 25387728.
2015
Age Differences in Prefrontal Surface Area and Thickness in Middle Aged to Older Adults.
Frontiers in aging neuroscience. 7 [DOI] 10.3389/fnagi.2015.00250. [PMID] 26834623.
2015
An observational study identifying obese subgroups among older adults at increased risk of mobility disability: do perceptions of the neighborhood environment matter?
The international journal of behavioral nutrition and physical activity. 12 [DOI] 10.1186/s12966-015-0322-1. [PMID] 26684894.
2015
Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults.
Journal of the American Heart Association. 4(2) [DOI] 10.1161/JAHA.114.001288. [PMID] 25696062.
2015
Associations Between Ankle-Brachial Index and Cognitive Function: Results From the Lifestyle Interventions and Independence for Elders Trial.
Journal of the American Medical Directors Association. 16(8):682-9 [DOI] 10.1016/j.jamda.2015.03.010. [PMID] 25869993.
2015
Correction: Light intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study.
PloS one. 10(4) [DOI] 10.1371/journal.pone.0126063. [PMID] 25875330.
2015
Cross-sectional and longitudinal risk of physical impairment in a cohort of postmenopausal women who experience physical and verbal abuse.
BMC women's health. 15 [DOI] 10.1186/s12905-015-0258-2. [PMID] 26554450.
2015
Geriatrics Consults Associated With Improved Mortality and Disposition in Hospitalized Elders
Journal of the American Geriatrics Society. 63(1, SI)
2015
Increased inflammation but similar physical composition and function in older-aged, HIV-1 infected subjects.
BMC immunology. 16 [DOI] 10.1186/s12865-015-0106-z. [PMID] 26204934.
2015
Interventions to reduce sedentary behavior.
Medicine and science in sports and exercise. 47(6):1306-10 [DOI] 10.1249/MSS.0000000000000519. [PMID] 25222818.
2015
Kaatsu training to enhance physical function of older adults with knee osteoarthritis: Design of a randomized controlled trial.
Contemporary clinical trials. 43:217-22 [DOI] 10.1016/j.cct.2015.06.016. [PMID] 26111922.
2015
Light Intensity physical activity and sedentary behavior in relation to body mass index and grip strength in older adults: cross-sectional findings from the Lifestyle Interventions and Independence for Elders (LIFE) study.
PloS one. 10(2) [DOI] 10.1371/journal.pone.0116058. [PMID] 25647685.
2015
Mitochondrial DNA Heteroplasmy Associations With Neurosensory and Mobility Function in Elderly Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(11):1418-24 [DOI] 10.1093/gerona/glv097. [PMID] 26328603.
2015
Physical activity behavior, barriers to activity, and opinions about a smartphone-based physical activity intervention among rural residents.
Telemedicine journal and e-health : the official journal of the American Telemedicine Association. 21(1):16-23 [DOI] 10.1089/tmj.2014.0034. [PMID] 25379976.
2015
Sedentary time is associated with the metabolic syndrome in older adults with mobility limitations–The LIFE Study.
Experimental gerontology. 70:32-6 [DOI] 10.1016/j.exger.2015.06.018. [PMID] 26130060.
2015
Successful aging: Advancing the science of physical independence in older adults.
Ageing research reviews. 24(Pt B):304-27 [DOI] 10.1016/j.arr.2015.09.005. [PMID] 26462882.
2015
The MAT-sf: identifying risk for major mobility disability.
The journals of gerontology. Series A, Biological sciences and medical sciences. 70(5):641-6 [DOI] 10.1093/gerona/glv003. [PMID] 25680917.
2015
Using physical activity to gain the most public health bang for the buck.
JAMA internal medicine. 175(6):968-9 [DOI] 10.1001/jamainternmed.2015.0544. [PMID] 25844886.
2014
Active muscle regeneration following eccentric contraction-induced injury is similar between healthy young and older adults.
Journal of applied physiology (Bethesda, Md. : 1985). 116(11):1481-90 [DOI] 10.1152/japplphysiol.01350.2012. [PMID] 23493365.
2014
Activity-related energy expenditure in older adults: a call for more research.
Medicine and science in sports and exercise. 46(12):2335-40 [DOI] 10.1249/MSS.0000000000000356. [PMID] 24714651.
2014
Change in physical activity after a diabetes diagnosis: opportunity for intervention.
Medicine and science in sports and exercise. 46(1):84-91 [DOI] 10.1249/MSS.0b013e3182a33010. [PMID] 23860414.
2014
Combined reduced forced expiratory volume in 1 second (FEV1) and peripheral artery disease in sedentary elders with functional limitations.
Journal of the American Medical Directors Association. 15(9):665-70 [DOI] 10.1016/j.jamda.2014.05.008. [PMID] 24973990.
2014
Diving below the surface of progressive disability: considering compensatory strategies as evidence of sub-clinical disability.
The journals of gerontology. Series B, Psychological sciences and social sciences. 69(2):263-74 [DOI] 10.1093/geronb/gbt110. [PMID] 24170713.
2014
Effect of dietary restriction and exercise on lower extremity tissue compartments in obese, older women: a pilot study.
The journals of gerontology. Series A, Biological sciences and medical sciences. 69(1):101-8 [DOI] 10.1093/gerona/gls337. [PMID] 23682155.
2014
Effect of structured physical activity on prevention of major mobility disability in older adults: the LIFE study randomized clinical trial.
JAMA. 311(23):2387-96 [DOI] 10.1001/jama.2014.5616. [PMID] 24866862.
2014
Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans.
Neurobiology of aging. 35(2):442.e1-8 [DOI] 10.1016/j.neurobiolaging.2013.05.023. [PMID] 24140124.
2014
Mobility Impairment and Recovery During Hospitalization in Older Adults
Journal of the American Geriatrics Society. 62(1, SI)
2014
Modifying effect of obesity on the association between sitting and incident diabetes in post-menopausal women.
Obesity (Silver Spring, Md.). 22(4):1133-41 [DOI] 10.1002/oby.20620. [PMID] 24123945.
2014
Obesity and late-age survival without major disease or disability in older women.
JAMA internal medicine. 174(1):98-106 [DOI] 10.1001/jamainternmed.2013.12051. [PMID] 24217806.
2014
Patterns of circulating inflammatory biomarkers in older persons with varying levels of physical performance: a partial least squares-discriminant analysis approach.
Frontiers in medicine. 1 [DOI] 10.3389/fmed.2014.00027. [PMID] 25593902.
2014
Psychological influences predict recovery following exercise induced shoulder pain.
International journal of sports medicine. 35(3):232-7 [DOI] 10.1055/s-0033-1345179. [PMID] 24022571.
2014
Respiratory impairment and dyspnea and their associations with physical inactivity and mobility in sedentary community-dwelling older persons.
Journal of the American Geriatrics Society. 62(4):622-8 [DOI] 10.1111/jgs.12738. [PMID] 24635756.
2014
Safety and metabolic outcomes of resveratrol supplementation in older adults: results of a twelve-week, placebo-controlled pilot study.
Experimental gerontology. 57:181-7 [DOI] 10.1016/j.exger.2014.05.015. [PMID] 24866496.
2014
Sedentary behavior and mortality in older women: the Women’s Health Initiative.
American journal of preventive medicine. 46(2):122-35 [DOI] 10.1016/j.amepre.2013.10.021. [PMID] 24439345.
2014
Simultaneous association of total energy consumption and activity-related energy expenditure with risks of cardiovascular disease, cancer, and diabetes among postmenopausal women.
American journal of epidemiology. 180(5):526-35 [DOI] 10.1093/aje/kwu152. [PMID] 25016533.
2014
The LIFE Cognition Study: design and baseline characteristics.
Clinical interventions in aging. 9:1425-36 [DOI] 10.2147/CIA.S65381. [PMID] 25210447.
2014
U.S. population estimates and correlates of sexual abuse of community-dwelling older adults.
Journal of elder abuse & neglect. 26(4):398-413 [DOI] 10.1080/08946566.2013.879845. [PMID] 24410194.
2013
Aging and muscle: a neuron’s perspective.
Current opinion in clinical nutrition and metabolic care. 16(1):21-6 [DOI] 10.1097/MCO.0b013e32835b5880. [PMID] 23222705.
2013
Aging, Aerobic Activity and Interhemispheric Communication
Journal of Cognitive Neuroscience.
2013
Chronic Resveratrol Supplementation and Brain Oxygenation: a Pilot Study
Gerontologist. 53(1)
2013
Comment: Consider Mechanical Efficiency and Comorbidity
Journal of Applied Physiology. 114:1117-1118
2013
Comments on point:counterpoint: skeletal muscle mechanical efficiency does/does not increase with age.
Journal of applied physiology (Bethesda, Md. : 1985). 114(8):1114-8 [DOI] 10.1152/japplphysiol.00185.2013. [PMID] 23588541.
2013
Comparison of Traditional and Task-Specific Exercise On Gait in the Pre-Clinically Disabled
Gerontologist. 53(1)
2013
Comparison of Traditional and Task-Specific Exercise On Gait in the Pre-Clinically Disabled
Gerontologist. 53(1)
2013
Designing pharmaceutical trials for sarcopenia in frail older adults: EU/US Task Force recommendations.
The journal of nutrition, health & aging. 17(7):612-8 [DOI] 10.1007/s12603-013-0362-7. [PMID] 23933872.
2013
Direct effects of leisure-time physical activity on walking speed.
The journal of nutrition, health & aging. 17(8):666-73 [DOI] 10.1007/s12603-013-0024-9. [PMID] 24097020.
2013
Effects of aerobic fitness on aging-related changes of interhemispheric inhibition and motor performance.
Frontiers in aging neuroscience. 5 [DOI] 10.3389/fnagi.2013.00066. [PMID] 24198784.
2013
Effects of Task-Specific and Traditional-Based Exercise in the Pre-Clinically Disabled: a Pilot Study
Gerontologist. 53(1)
2013
Functional language networks in sedentary and physically active older adults.
Journal of the International Neuropsychological Society : JINS. 19(6):625-34 [DOI] 10.1017/S1355617713000246. [PMID] 23458438.
2013
Life-Cognition: Design and Baseline Data
Gerontologist. 53(1)
2013
Longitudinal change in energy expenditure and effects on energy requirements of the elderly.
Nutrition journal. 12 [DOI] 10.1186/1475-2891-12-73. [PMID] 23742706.
2013
Lumbar Muscle Activity During Common Lifts: a Preliminary Study Using Magnetic Resonance Imaging
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2013
Lumbar muscle activity during common lifts: a preliminary study using magnetic resonance imaging.
Journal of applied biomechanics. 29(2):147-54 [PMID] 22814283.
2013
Metabolic Rate of Walking in Fatigued Vs. Non-Fatigued Older Adults
Gerontologist. 53(1)
2013
Mitochondrial Function and Fatigability in Older Adults Who Report Severe Fatigue
Gerontologist. 53(1)
2013
Mobility decline in old age: a time to intervene.
Exercise and sport sciences reviews. 41(1) [DOI] 10.1097/JES.0b013e318279fdc5. [PMID] 23262463.
2013
Neuromuscular determinants of maximum walking speed in well-functioning older adults.
Experimental gerontology. 48(3):358-63 [DOI] 10.1016/j.exger.2013.01.010. [PMID] 23376102.
2013
Prestroke factors associated with poststroke mortality and recovery in older women in the Women’s Health Initiative.
Journal of the American Geriatrics Society. 61(8):1324-30 [DOI] 10.1111/jgs.12361. [PMID] 23869842.
2013
Promoting physical activity for elders with compromised function: the lifestyle interventions and independence for elders (LIFE) study physical activity intervention.
Clinical interventions in aging. 8:1119-31 [DOI] 10.2147/CIA.S49737. [PMID] 24049442.
2013
Sedentary Behavior and Mortality in Older Women
The FASEB's Journal. 27
2013
Skeletal muscle mitochondrial energetics are associated with maximal aerobic capacity and walking speed in older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 68(4):447-55 [DOI] 10.1093/gerona/gls196. [PMID] 23051977.
2013
Snoring, daytime sleepiness, and incident cardiovascular disease in the health, aging, and body composition study.
Sleep. 36(11):1737-45 [DOI] 10.5665/sleep.3140. [PMID] 24179308.
2013
WHAT WE HAVE LEARNED FROM EXERCISE AND LIFESTYLE TRIALS TO ALLEVIATE MOBILITY IMPAIRMENT IN OLDER ADULTS.
The Journal of frailty & aging. 2(1):57-9 [PMID] 26568947.
2012
Accuracy of Perceived Exertion in Older Adults Performing Common Daily Tasks
Medicine and Science in Sports and Exercise. 44
2012
Age-related differences in lower extremity tissue compartments and associations with physical function in older adults.
Experimental gerontology. 47(1):38-44 [DOI] 10.1016/j.exger.2011.10.001. [PMID] 22015325.
2012
Aging, aerobic activity and interhemispheric communication.
Brain sciences. 2(4):634-48 [DOI] 10.3390/brainsci2040634. [PMID] 24961264.
2012
Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exercise.
Journal of the American Geriatrics Society. 60(7):1244-52 [DOI] 10.1111/j.1532-5415.2012.04045.x. [PMID] 22726232.
2012
Blood flow restriction enhances post-resistance exercise angiogenic gene expression.
Medicine and science in sports and exercise. 44(11):2077-83 [DOI] 10.1249/MSS.0b013e3182625928. [PMID] 22677927.
2012
Blood Flow Restriction Increases Angiogenic Gene Expression in Skeletal Muscle Following Acute Resistance Exercise
Medicine and Science in Sports and Exercise. 44
2012
Cognition Results From the Resveratrol for Improved Performance in Elders (Ripe) Trial
Gerontologist. 52
2012
Cognitive and Structural Brain Correlates of Physical Activity and Fitness in Healthy Aging
Gerontologist. 52
2012
Commentaries on Viewpoint: Muscle atrophy is not always sarcopenia.
Journal of applied physiology (Bethesda, Md. : 1985). 113(4):680-4 [DOI] 10.1152/japplphysiol.00667.2012. [PMID] 22896680.
2012
Design and Rationale for a Long-Term Study of Physical Activity in Older Adults
Gerontologist. 52
2012
Dynapenia and aging: an update.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(1):28-40 [DOI] 10.1093/gerona/glr010. [PMID] 21444359.
2012
Factors Associated With Survival After Stroke Among Elderly Women in the Whi.
Journal of the American Geriatrics Society. 60
2012
Growth hormone responses to acute resistance exercise with vascular restriction in young and old men.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 22(5):167-72 [DOI] 10.1016/j.ghir.2012.05.002. [PMID] 22727808.
2012
Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderly.
Biochimica et biophysica acta. 1817(9):1691-700 [PMID] 22659402.
2012
Obesity and use of compensatory strategies to perform common daily activities in pre-clinically disabled older adults.
Archives of gerontology and geriatrics. 54(2):e134-8 [DOI] 10.1016/j.archger.2011.10.017. [PMID] 22209394.
2012
On Muscle Atrophy, Aging, and Disease
Journal of Applied Physiology. 113
2012
Pain-related fear and catastrophizing predict pain intensity and disability independently using an induced muscle injury model.
The journal of pain. 13(4):370-8 [DOI] 10.1016/j.jpain.2011.12.011. [PMID] 22424914.
2012
Performance and Perceived Fatigability in Older Adults Who Self-Report Severe Fatigue
Gerontologist. 52
2012
Relation of pulse pressure to long-distance gait speed in community-dwelling older adults: findings from the LIFE-P study.
PloS one. 7(11) [DOI] 10.1371/journal.pone.0049544. [PMID] 23185357.
2012
Role of self-efficacy (SE) and anxiety among pre-clinically disabled older adults when using compensatory strategies to complete daily tasks.
Archives of gerontology and geriatrics. 55(3):611-24 [DOI] 10.1016/j.archger.2012.06.007. [PMID] 22770713.
2012
Skeletal muscle apoptotic signaling predicts thigh muscle volume and gait speed in community-dwelling older persons: an exploratory study.
PloS one. 7(2) [DOI] 10.1371/journal.pone.0032829. [PMID] 22389725.
2012
The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals.
Aging cell. 11(5):801-9 [DOI] 10.1111/j.1474-9726.2012.00844.x. [PMID] 22681576.
2012
Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia.
The journals of gerontology. Series A, Biological sciences and medical sciences. 67(1):17-27 [DOI] 10.1093/gerona/glr042. [PMID] 21636833.
2012
What is dynapenia?
Nutrition (Burbank, Los Angeles County, Calif.). 28(5):495-503 [DOI] 10.1016/j.nut.2011.12.002. [PMID] 22469110.
2011
Activity energy expenditure and incident cognitive impairment in older adults.
Archives of internal medicine. 171(14):1251-7 [DOI] 10.1001/archinternmed.2011.277. [PMID] 21771893.
2011
An exploratory analysis of the effects of a weight loss plus exercise program on cellular quality control mechanisms in older overweight women.
Rejuvenation research. 14(3):315-24 [DOI] 10.1089/rej.2010.1132. [PMID] 21631380.
2011
Commentaries on Viewpoint: Expending our physical activity (measurement) budget wisely.
Journal of applied physiology (Bethesda, Md. : 1985). 111(2) [DOI] 10.1152/japplphysiol.00650.2011. [PMID] 21828253.
2011
Development of physical disability in older adults.
Current aging science. 4(3):184-91 [PMID] 21529321.
2011
Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial.
Clinical interventions in aging. 6:141-9 [DOI] 10.2147/CIA.S17001. [PMID] 21753869.
2011
European ancestry and resting metabolic rate in older African Americans.
European journal of clinical nutrition. 65(6):663-7 [DOI] 10.1038/ejcn.2011.22. [PMID] 21468093.
2011
Metabolic cost of daily activities and effect of mobility impairment in older adults.
Journal of the American Geriatrics Society. 59(11):2118-23 [DOI] 10.1111/j.1532-5415.2011.03655.x. [PMID] 22091979.
2011
Mitochondrial DNA variation in human metabolic rate and energy expenditure.
Mitochondrion. 11(6):855-61 [DOI] 10.1016/j.mito.2011.04.005. [PMID] 21586348.
2011
Myogenic and proteolytic mRNA expression following blood flow restricted exercise.
Acta physiologica (Oxford, England). 201(2):255-63 [DOI] 10.1111/j.1748-1716.2010.02172.x. [PMID] 20653608.
2011
Physical activity and neural correlates of aging: a combined TMS/fMRI study.
Behavioural brain research. 222(1):158-68 [DOI] 10.1016/j.bbr.2011.03.042. [PMID] 21440574.
2011
Relative safety of 4 weeks of blood flow-restricted resistance exercise in young, healthy adults.
Scandinavian journal of medicine & science in sports. 21(5):653-62 [DOI] 10.1111/j.1600-0838.2010.01100.x. [PMID] 21917016.
2011
The impact of behavioral intervention on obesity mediated declines in mobility function: implications for longevity.
Journal of aging research. 2011 [DOI] 10.4061/2011/392510. [PMID] 22013527.
2011
Validation of an armband to measure daily energy expenditure in older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 66(10):1108-13 [DOI] 10.1093/gerona/glr101. [PMID] 21734231.
2010
Acute Systemic Growth Responses To Low Intensity Blood Flow Restricted Resistance Exercise in Old Men
Medicine and Science in Sports and Exercise. 42
2010
Effects of age and sedentary lifestyle on skeletal muscle NF-kappaB signaling in men.
The journals of gerontology. Series A, Biological sciences and medical sciences. 65(5):532-7 [DOI] 10.1093/gerona/glp196. [PMID] 20045871.
2010
Effects of exercise on mobility in obese and nonobese older adults.
Obesity (Silver Spring, Md.). 18(6):1168-75 [DOI] 10.1038/oby.2009.317. [PMID] 19834467.
2010
Energy expenditure and aging.
Ageing research reviews. 9(1):1-11 [DOI] 10.1016/j.arr.2009.08.002. [PMID] 19698803.
2010
European Ancestry and Resting Metabolic Rate in Older Persons
Gerontologist. 50
2010
Fibrinogen, D-Dimer and Tpa Antigen Concentrations Following Acute and Chronic Blood Flow Restricted Resistance Exercise
Medicine and Science in Sports and Exercise. 42
2010
Functional consequences of sarcopenia and dynapenia in the elderly.
Current opinion in clinical nutrition and metabolic care. 13(3):271-6 [DOI] 10.1097/MCO.0b013e328337819e. [PMID] 20154609.
2010
Measuring balance, lower extremity strength and gait in the elderly: construct validation of an instrument.
Archives of gerontology and geriatrics. 51(2):199-204 [DOI] 10.1016/j.archger.2009.10.008. [PMID] 19914723.
2010
Mitochondrial Dna Variation in Human Metabolic Rate, Energy Expenditure and Mortality: the Health, Aging and Body Composition Study
Genetic Epidemiology. 34
2010
Models of accelerated sarcopenia: critical pieces for solving the puzzle of age-related muscle atrophy.
Ageing research reviews. 9(4):369-83 [DOI] 10.1016/j.arr.2010.04.004. [PMID] 20438881.
2010
Relationship between physical functioning and physical activity in the lifestyle interventions and independence for elders pilot.
Journal of the American Geriatrics Society. 58(10):1918-24 [DOI] 10.1111/j.1532-5415.2010.03008.x. [PMID] 20738437.
2010
Sedentary individuals as “controls” in human studies: the correct approach?
Proceedings of the National Academy of Sciences of the United States of America. 107(34) [DOI] 10.1073/pnas.1008118107. [PMID] 20660311.
2010
The Effect of Functional Circuit Training On Balance and Strength in Physically Frail Older Adults
Medicine and Science in Sports and Exercise. 42
2010
The effect of functional circuit training on physical frailty in frail older adults: a randomized controlled trial.
Journal of aging and physical activity. 18(4):401-24 [PMID] 20956842.
2009
Activity energy expenditure and change in body composition in late life.
The American journal of clinical nutrition. 90(5):1336-42 [DOI] 10.3945/ajcn.2009.27659. [PMID] 19740971.
2009
Activity energy expenditure and mobility limitation in older adults: differential associations by sex.
American journal of epidemiology. 169(12):1507-16 [DOI] 10.1093/aje/kwp069. [PMID] 19383938.
2009
Blood flow restricted exercise and skeletal muscle health.
Exercise and sport sciences reviews. 37(2):78-85 [DOI] 10.1097/JES.0b013e31819c2e5c. [PMID] 19305199.
2009
Delayed-onset muscle soreness induced by low-load blood flow-restricted exercise.
European journal of applied physiology. 107(6):687-95 [DOI] 10.1007/s00421-009-1175-6. [PMID] 19727801.
2009
Effects of Lifestyle Modification On Muscle Strength and Quality in Obese Older Adults
Gerontologist. 49
2009
Longitudinal study of muscle strength, quality, and adipose tissue infiltration.
The American journal of clinical nutrition. 90(6):1579-85 [DOI] 10.3945/ajcn.2009.28047. [PMID] 19864405.
2009
Organ-o-penia.
Journal of applied physiology (Bethesda, Md. : 1985). 106(6):1759-60 [DOI] 10.1152/japplphysiol.00315.2009. [PMID] 19359616.
2009
Physical activity and maintaining physical function in older adults.
British journal of sports medicine. 43(1):28-31 [DOI] 10.1136/bjsm.2008.053736. [PMID] 18927164.
2009
Restoration of voluntary muscle strength after 3 weeks of cast immobilization is suppressed in women compared with men.
Archives of physical medicine and rehabilitation. 90(1):178-80 [DOI] 10.1016/j.apmr.2008.06.032. [PMID] 19154845.
2009
Sarcopenia: clinical evaluation, biological markers and other evaluation tools.
The journal of nutrition, health & aging. 13(8):724-8 [PMID] 19657557.
2008
Activity Energy Expenditure and the Change in Body Composition During Late Life
Medicine and Science in Sports and Exercise. 40(5) [DOI] 10.1249/01.mss.0000323061.63373.e2.
2008
Association of the ACTN3 genotype and physical functioning with age in older adults.
The journals of gerontology. Series A, Biological sciences and medical sciences. 63(11):1227-34 [PMID] 19038838.
2008
Energy Metabolism and the Change in Body Composition During Late Life
Gerontologist. 48
2008
Energy Metabolism: Associations With Age, Fatigue and Activity
Gerontologist. 48
2008
Modulation of age-induced apoptotic signaling and cellular remodeling by exercise and calorie restriction in skeletal muscle.
Free radical biology & medicine. 44(2):160-8 [DOI] 10.1016/j.freeradbiomed.2007.05.028. [PMID] 18191752.
2008
Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study.
BMC geriatrics. 8 [DOI] 10.1186/1471-2318-8-34. [PMID] 19102751.
2008
Recovering From Mobility Limitation: a Common Practice Among Older Adults
Journal of the American Geriatrics Society. 56:S176-S177
2008
Sarcopenia =/= dynapenia.
The journals of gerontology. Series A, Biological sciences and medical sciences. 63(8):829-34 [PMID] 18772470.
2007
Effect of prolonged unweighting of human skeletal muscle on neuromotor force control.
European journal of applied physiology. 100(1):53-62 [PMID] 17287986.
2007
Efficacy of resistance and task-specific exercise in older adults who modify tasks of everyday life.
The journals of gerontology. Series A, Biological sciences and medical sciences. 62(6):616-23 [PMID] 17595417.
2007
Fatigue-induced changes in phasic muscle activation patterns during dynamic trunk extension exercise.
American journal of physical medicine & rehabilitation. 86(5):373-379 [DOI] 10.1097/PHM.0b013e3180321689. [PMID] 17303959.
2007
Knee extension strength cutpoints for maintaining mobility.
Journal of the American Geriatrics Society. 55(3):451-7 [PMID] 17341251.
2007
Reduced physical activity increases intermuscular adipose tissue in healthy young adults.
The American journal of clinical nutrition. 85(2):377-84 [PMID] 17284732.
2006
Adaptations in human neuromuscular function following prolonged unweighting: II. Neurological properties and motor imagery efficacy.
Journal of applied physiology (Bethesda, Md. : 1985). 101(1):264-72 [PMID] 16514003.
2006
Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms’ tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research. 12(24):7284-93 [PMID] 17189400.
2006
Daily activity energy expenditure and mortality among older adults.
JAMA. 296(2):171-9 [PMID] 16835422.
2006
Evaluating task modification as an objective measure of functional limitation: repeatability and comparability.
The journals of gerontology. Series A, Biological sciences and medical sciences. 61(7):718-25 [PMID] 16870635.
2006
Midlife physical activity and mobility in older age: The InCHIANTI study.
American journal of preventive medicine. 31(3):217-24 [PMID] 16905032.
2005
Knee extensor isometric unsteadiness does not predict functional limitation in older adults.
American journal of physical medicine & rehabilitation. 84(2):112-21 [PMID] 15668559.
2005
Misconceptions about strength exercise among older adults.
Journal of aging and physical activity. 13(4):422-33 [PMID] 16301754.
2005
Resistance and functional training reduces knee extensor position fluctuations in functionally limited older adults.
European journal of applied physiology. 95(5-6):436-46 [PMID] 16193338.
2005
Sex differences in muscle fatigability and activation patterns of the human quadriceps femoris.
European journal of applied physiology. 94(1-2):196-206 [PMID] 15791418.
2004
Leg muscle activity during walking with assistive devices at varying levels of weight bearing.
Archives of physical medicine and rehabilitation. 85(9):1555-60 [PMID] 15375835.
2003
Derecruitment of the lumbar musculature with fatiguing trunk extension exercise.
Spine. 28(3):282-7 [PMID] 12567032.
2003
Gender differences in skeletal muscle fatigability are related to contraction type and EMG spectral compression.
Journal of applied physiology (Bethesda, Md. : 1985). 94(6):2263-72 [PMID] 12576411.
2002
Electromyographic activity of the lumbar and hip extensors during dynamic trunk extension exercise.
Archives of physical medicine and rehabilitation. 83(11):1547-52 [PMID] 12422323.
2002
Electromyographic activity of the trunk extensor muscles: effect of varying hip position and lumbar posture during Roman chair exercise.
Archives of physical medicine and rehabilitation. 83(11):1543-6 [PMID] 12422322.
2002
Functionally relevant thresholds of quadriceps femoris strength.
The journals of gerontology. Series A, Biological sciences and medical sciences. 57(4):B144-52 [PMID] 11909879.

Grants

Jun 2024 ACTIVE
Testing the Pain Relief of musculOskeletal conditions and Arthritis using Culturally Tailored InterVentions for Black Elders (PROACTIVE) Intervention: A Randomized Controlled Trial
Role: Project Manager
Funding: NATL INST OF HLTH NINR
Apr 2023 ACTIVE
The impact of structural racism and discrimination on chronic pain in Black or African American older adults: Biopsychosocial mechanisms
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Sep 2022 ACTIVE
Functional Decline in Low Functioning Older Adults; Role of iron dysregulation
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Jun 2022 ACTIVE
University of Florida Claude D. Pepper Older Americans Independence Center
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jun 2022 ACTIVE
ROAMM-EHR: Pilot Trial of a Real-Time Symptom Surveillance System for Post-Discharge Surgical Patients
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jun 2022 ACTIVE
Biopsychosocial pain predictors of mobility decline in aging
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
May 2022 – May 2024
Assessment of Cortical Bone Mechanics Technology (CBMT) Fracture Discrimination Capability
Role: Principal Investigator
Funding: OsteoDx via NATL INST OF HLTH NIA
Apr 2022 ACTIVE
Wearable Technology Infrastructure to Enhance Capacity for Real-Time, Online Assessment and Mobility (ROAMM) of Intervening Health Events in Older Adults
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Jan 2022 ACTIVE
OneFlorida+ Phase 3 Clinical Research Network
Role: Co-Investigator
Funding: PATIENT-CENTERED OUTCOMES RES INST
Sep 2021 ACTIVE
Multi-Stakeholder Engagement for Interdisciplinary Telehealth in Lewy Body Dementia
Role: Other
Funding: NATL INST OF HLTH NIA
May 2021 – Oct 2022
Preventing the Calcium Channel Blocker Lower Extremity Edema Loop Diuretic Prescribing Cascade in Older Adults
Role: Other
Funding: NATL INST OF HLTH NIA
Feb 2021 – Jan 2024
Empowering the Management of Pain-Obesity-Weight through Enhanced Reward
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Jun 2020 – May 2023
Coordinating Center of the Claude D. Pepper Older Americans Independence Centers
Role: Principal Investigator
Funding: WAKE FOREST UNIV via NATL INST OF HLTH NIA
May 2020 ACTIVE
Translational Research Training on Aging and Mobility (TRAM)
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Feb 2020 – Jan 2024
Investigating Movement-evoked Pain in osteoArthritic Conditions (IMPACT): An Observational Study to Inform Culturally-Tailored Intervention Development
Role: Other
Funding: NATL INST OF HLTH NIAMS
Mar 2019 – Feb 2022
Wearable Technology Infrastructure to Enhance Capacity for Real-Time, Online Assessment and Mobility (ROAMM) of Intervening Health Events in Older Adults
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2018 ACTIVE
Multimodal imaging of brain activity to investigate walking and mobility decline in older adults
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Aug 2018 – Apr 2023
INTERmittent pneumatic ComprEssion for Disablility rEversal in PAD: the INTERCEDE Trial
Role: Faculty
Funding: NORTHWESTERN UNIV via NATL INST OF HLTH NIA
Sep 2017 – May 2024
The University of Florida Jacksonville Aging Studies Center (JAX-ASCENT)
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Sep 2017 – May 2020
The acute development and persistence of frailty, comorbidity and disability in critically ill elderly patients after severe traumatic injury: induced frailty
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
Apr 2017 – Mar 2022
University of Florida Claude D. Pepper Older Americans Independence Center (OAIC)
Role: Other
Funding: NATL INST OF HLTH NIA
Dec 2016 – Sep 2023
MoTrPAC Consortium Coordinating Center
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Apr 2016 – Mar 2017
Claude D Pepper Older Americans Independence Center
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Jan 2016 – Dec 2021
ufhcc-ioa cancer-aging collaborative team grants
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Sep 2015 – Jun 2018
Muscle mass and strength cut-points associated with mobility limitation in older adults
Role: Principal Investigator
Funding: BRIGHAM AND WOMENS HOSPITAL via NATL INST OF HLTH NIA
Sep 2015 – Mar 2018
PEAKS: Validation of mobile technologies for clinical assessment, monitoring, and intervention
Role: Principal Investigator
Funding: EVERYFIT INC via NATL INST OF HLTH
Sep 2015 – May 2021
The ENRGISE Study
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Apr 2015 – Jan 2019
Low intensity exercise intervention in peripheral artery disease
Role: Co-Investigator
Funding: NORTHWESTERN UNIV via NATL INST OF HLTH NHLBI
Apr 2015 – Mar 2017
A pilot study to evaluate the role of brain integrity on post-hospital sarcopenia
Role: Principal Investigator
Funding: UF FOUNDATION
Apr 2015 – Mar 2016
Claude D. Pepper Older Americans Independence Center
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Sep 2014 – Apr 2017
Measuring Cognitive Fatigability in Older Adults
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Sep 2014 – Jan 2019
Neural Mechanisms of Dynapenia
Role: Principal Investigator
Funding: OHIO UNIV via NATL INST OF HLTH NIA
Jul 2014 – Jul 2024
CARDIOPULMONARY EXERCISE TESTING EQUIPMENT (MV02) OPERATING ACCOUNT
Role: Principal Investigator
Funding: 214 OPERATING ACCOUNT
Feb 2014 – Feb 2016
Sarcopenic transitions for predicting physical disability states
Role: Principal Investigator
Funding: SANOFI US SERVICES
Jan 2014 – Dec 2018
MtDNA variant modifiers of cardiopulmonary responsiveness to physical activity
Role: Principal Investigator
Funding: NATL INST OF HLTH NHLBI
Sep 2013 ACTIVE
COM Deans Commitment Matching Funds for UF OAIC
Role: Principal Investigator
Funding: FL CLINICAL PRACTICE ASSO
Sep 2013 – Dec 2019
REVIVE – Resveratrol to enhance vitality and vigor in elders
Role: Co-Investigator
Funding: NATL CTR FOR COMPLEM AND INTEGRATIVE HLT
Jul 2013 – Mar 2019
Metabolic Costs of Daily Activities in Older Adults
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Sep 2011 – Nov 2018
The LIFE Study
Role: Project Manager
Funding: NATL INST OF HLTH NIA
Jul 2006 – Dec 2020
21st Century Research & Economic Development Investment Program (REDIP)
Role: Project Manager
Funding: STATE UNIV SYS OF FL BOARD OF GOVERNORS

Education

Post-Doc in Epidemiology
2006 · National Institute on Aging
PhD in Geriatric Exercise Physiology
2004 · Syracuse University
Certificate of Advanced Study in Gerontology
2001 · Syracuse University
Masters of Science in Exercise Physiology
2000 · Syracuse University
Bachelors of Science in Biology
1997 · Ohio University

Contact Details

Phones:
Business:
(352) 273-5914
Emails:
Business:
tmanini@ufl.edu
Addresses:
Business Mailing:
PO Box 100147
GAINESVILLE FL 32610
Business Street:
1889 MUSEUM RD STE 7000 FL 7
Gainesville FL 32611